Juventus are currently leading second-placed Napoli in the Serie A by six points and will play Walter Mazzarri's side on Saturday at Stadio San Paolo.
Bonucci is confident that Juve will be able to build on their 3-0 win over Siena last weekend to beat Napoli and extend their lead to nine points in the Serie A table.
"Getting the victory against a good Siena side was crucial," he wrote on his official website.
"Now we have a six-point advantage over Napoli and it must give us confidence for the trip to the San Paolo.
"We are going to Napoli in order to win and play our most important game of the season. That is our objective, to be Juventus."
Juventus defeated Napoli 2-0 in the reverse fixture earlier this season.