Ferrara left his position as the boss of Italy's Under-21 team to return to club management.
"I would like to thank the club for the great opportunity handed to me," Ferrara said in today's press conference.
"I don't think there could have been a better solution for me professionally and personally.
"I have spent two splendid years working for the (Italian Football) federation and I thank them for allowing me to join Sampdoria.
"This experience has given me so much. I have regained the enthusiasm, motivation that pushed me to come to Sampdoria.
"I accepted Sampdoria's offer because this is a serious club and I was attracted by their project. I am very happy.
"I hope I can achieve the aims set by the club."
The 45-year-old Ferrara replaced Giuseppe Iachini, who recently led the Genoa outfit to promotion to Italy's top flight via the play-offs.
"Our aim this season is to remain in Serie A without major scares," the former Juventus tactician said.
"I will need time to get to know my players.
"As for the transfer market, I think this year will be more difficult than in the past."
Ferrara, who signed a two-year contract with the Partenopei outfit, will coach a club for the first time since a spell at Juventus in the 2009-10 campaign.
Sampdoria begin pre-season training on July 15 in Bardonecchia, Turin.