Defending Serie A champions Milan released older players like Andrea Pirlo and Massimo Oddo over the summer, while bringing in established talents like Taye Taiwo, Antonio Nocerino and Alberto Aquilani.
In comparison, Inter sold Samuel Eto'o to Anzhi Makhachkala but left it late to bring in his replacement after their reported protracted interest in Carlos Tevez didn't materialise into a concrete bid.
They signed 32-year-old Diego Forlan, who is cup tied after playing for Atletico Madrid in the Europa League, in the last day of the transfer window and also brought in Mauro Zarate on deadline day from Lazio.
Moggi feels that Milan's shrewd business dealings have put them in prime position to defend their Serie A title.
He told Radio Mana Mana Sport: "Milan are light years ahead compared to the rest,
"I have doubts Inter will do well because of the way they operated on the transfer market. They bought badly and I don't think they will be competitive.
"Milan, on the other hand, did well on the transfer market and they showed logic in terms of how they shaped their group of players."
In the first match of the new Serie A season, Milan play Lazio on Friday night at San Siro, while Inter travel to Palermo for their Serie A kick-off on Sunday evening.