With the new season beginning this weekend, Milan's derby rival Inter Milan have the problem of coping with the departure of striker Samuel Eto'o, as well as the arrival of new coach Gian Piero Gasperini.
Milan, on the other hand, remain largely unchanged since the last season, and have already beaten Inter 2-1 in the recent Italian Super Cup.
"Inter remains our most dangerous opponent, but we're still the favourites for the title," Milan coach Massimiliano Allegri was quoted in the Sunday Tribune.
"When we decide to play, we're capable of beating anyone."
Eto'o's record 20 million € per season deal with Russin club Anzhi Makhachkala is set to make him the highest paid footballer in the world.
Having scored 37 goals for Inter in all competitions last season, Milan forward Zlatan Ibrahimovic believes Inter are "losing a lot of quality".
"There are not many players like him. He's one of the best."
Atletico's Diego Forlan, Napoli's Ezequiel Lavezzi or Manchester City's Carlos Tevez are Inter's next targets as Eto'o's replacement.
Inter president Massimo Moratti has claimed that the move was made due to changes in UEFA's financial fair play standards, and believes that the riled fans will calm down.
"The fans were also upset when Ibrahimovic left Inter, but then look how that ended up," Moratti said, remembering Ibrahimovi's departure for Barcelona before Inter won their first consecutive Serie A and 2009-10 Champions League titles. The player returned with Milan to Italy just a year later.
Milan will open at Cagliari on Saturday, with Inter hosting Lecce on Sunday.