The Giallorossi head into the clash at the Marc' Antonio Bentegodi stadium on the back of a triumph against Juventus in midweek.
Roma, who beat Livorno 3-0 on Saturday, followed that up with a 1-0 victory against their scudetto rivals to reach the semi-finals of the Coppa Italia.
The Eternal City giants will face the winners of next week's quarter-final tie between Napoli and Lazio.
"There are many good sides left in the Coppa and between Napoli and Lazio there is very little difference," Roma coach Rudi Garcia said.
"Right now our focus is on our next game against Verona."
Tuesday's victory, courtesy of Gervinho's solitary goal, allowed Roma to avenge their 3-0 loss at Juventus in the league earlier this month.
The Giallorossi have won all of their games since and not conceded a goal in the process.
"We wanted to bounce back from our defeat in Turin and we proved to be at the same level as Juve," Roma captain Francesco Totti said. "In my opinion, there is not much difference between us and them even though they have a good lead in Serie A."
Roma trail eight points behind Serie A leaders Juve, who visit Lazio on Saturday.
Hellas Verona goalkeeper Rafael believes his team must have a flawless game if it is to surprise Roma.
The Verona outfit goes into the encounter on the back of two straight losses.
Andrea Mandorlini's men fell 3-0 to Napoli before losing 1-0 at AC Milan last time out.
"We expect a very difficult game against Roma," Rafael said. "We simply cannot make any mistakes.
"We face a great side and the strongest Totti I have seen."
Hellas are sixth in the standings, level on 32 points with Inter Milan, who are fifth.
The hosts will be bolstered by the return of the team's top scorer Luca Toni. He missed last weekend's match through injury.