New Sevilla coach Unai Emery, who led his side to a 3-0 victory over Granada in league action on Monday night, believes his side must "recover quickly" to stand any chance of a positive result against Atletico.
Emery will monitor the fitness of goalkeeper Andres Palop, who missed the Granada game, with Julian primed to feature if he does not recover. Alberto Moreno and Juan Cala (both calf) could return to the squad for the match at the Vicente Calderon.
Atletico striker Radamel Falcao did not train with the main group on Tuesday as he continues his recovery from a hamstring injury, while defender Domingo Cisma was not involved due to a right ankle problem.
Real Madrid and Barcelona have it all to play for in the second leg of their Copa del Rey semi-final after an entertaining 1-1 draw at the Bernabeu on Wednesday.
Both sides had plenty of chances during an enthralling first half but the opener did not arrive until five minutes into the second period when Cesc Fabregas latched onto Lionel Messi's through ball to fire past Diego Lopez.
Madrid got the equaliser their performance merited nine minutes from time when the game's outstanding performer, Raphael Varane, rose to head home Mesut Ozil's cross.
Thursday's Copa del Rey Semi-final First Leg Fixtures
Atletico Madrid vs Sevilla
Wednesday's Copa del Rey Semi-final First Leg Results