With Manchester United crowned champions weeks ago, manager Sir Alex Ferguson heading off into retirement and the three relegation places now finalised, for once there is little to resolve in the denouement to the campaign.
It means the focal point to Sunday's four o'clock showdowns will be three London clubs - Chelsea, Arsenal and Tottenham - and their scrap for Champions League football, and the riches it brings.
In his final game in charge of Chelsea in his role as interim manager, and presumably before Jose Mourinho returns, Rafael Benitez faces Everton at Stamford Bridge.
The Blues, barring a mathematical miracle regarding goal difference, are assured of their return to Europe's top table after their heroics in lifting the Europa League trophy in midweek.
Arsene Wenger's Arsenal, meanwhile, face a Newcastle side now resting easy in the wake of Wigan's 4-1 loss at the Emirates on Tuesday that condemned the Latics to the drop, sparing the handful of clubs above them a potentially harrowing final day.
Chelsea and Arsenal, though, face a bizarre scenario where both clubs could end up in a dead-heat for third position, tied on points, goal difference and goals scored.
Should Chelsea draw and Arsenal win by the odd goal, and score two more goals than the Blues in the process (ie 0-0 and 2-1, or 1-1 and 3-2), they would be tied.
To determine which club clinches the third automatic Champions League spot, and which would go into the qualifying round, they would have a play-off game.
For Chelsea goalkeeper Petr Cech, that is frustrating given Chelsea have beaten Arsenal home and away in the league this season, a rule not applicable to the Premier League, unlike in Europe.
"I know this is the rule, but we beat them twice over the course of the season, so a play-off would be really extraordinary," said Cech.
"The rules are like that. Hopefully it won't happen for both of us."
As for Tottenham, they host Sunderland, another of the clubs now safe from the drop courtesy of Wigan's demise at Arsenal.
Andre Villas-Boas' side have to beat the Black Cats and hope Arsenal either lose or draw against the Magpies at St James' Park.
And Spurs cannot expect Sunderland to roll over given manager Paolo Di Canio has warned his players their holidays will be cut short if they do not bow out with anything other than pride in their display.
Other than that, there is only prize money at stake, but then given the difference between 11th-placed Stoke and 17th-placed Sunderland - separated by just two points - is £4.5million, that is not to be sniffed at.
Of the other clubs in those positions, other than the north-east duo, Stoke and Southampton clash at St Mary's, which could be manager Mauricio Pochettino's last match in charge given the doubts over chairman Nicola Cortese's future.
Twelfth-placed Norwich travel to managerless Manchester City, Fulham in 15th take on Swansea at the Liberty Stadium, whilst Aston Villa, currently 16th, are also on the road at Wigan.
The minor squabble for the bottom two places sees QPR at Liverpool and Reading at West Ham, who may need a win to confirm a top-half-of-the-table spot.
As for Ferguson, he bows out after a phenomenal 26 and a half years in charge as Manchester United boss, with a game at The Hawthorns again West Brom.
Sunday's Premier League Fixtures
Chelsea vs Everton
Liverpool vs QPR
Man City vs Norwich
Newcastle vs Arsenal
Southampton vs Stoke
Swansea vs Fulham
Tottenham vs Sunderland
West Brom vs Man United
West Ham vs Reading
Wigan vs Aston Villa