"It was a really sad day when Sir Alex told us what was happening," said Van Persie.
"But everyone understands it and from my point of view it has been a great honour.
"One year is not a lot but he is a great manager and a great person. The way he handles players is unbelievable."
Ferguson was not the only person to bid farewell to Old Trafford.
As is his style, Scholes disappeared into the shadows quietly, having returned to the fray for his farewell appearance after a three-and-a-half month absence.
But in the same way as Ferguson made his mark on Van Persie, so did 38-year-old Scholes.
"Scholesy is unbelievable," said Van Persie.
"When I first came to England I saw things I never saw before from players like Bergkamp, Henry and Pires.
"Since I came here, I have that feeling again. Scholesy can do things I have never seen in my life."
It will be left to players like Van Persie to maintain United's status as a winning machine under Moyes, although the Dutchman does not think that will be a problem.
"That is what this club is about," he said.
"This club will always be here and will always fight for trophies."