By FOX Sports Staff
The two will be on the touchline when their sides clash at Old Trafford on Sunday night.
Tensions between the two ratcheted during the 2008/09 campaign when Benitez's Liverpool side were the closest challengers to United who ultimately won their 18th league title by four points.
At the time, the Spaniard even claimed that many of the Premier League referees appeared to be giving decisions in favour of Ferguson's team while the United chief has even resorted to snubbing the Spaniard's offer of a handshake during the games between the two sides.
The relationship between the two has improved somewhat this season as Benitez's Chelsea side have not posed a direct threat to United's title charge even though the Blues have knocked out United from both domestic cup competitions.
On Sunday though, the stakes will certainly be higher for Chelsea with the London outfit needing the three points in their bid to secure a top-four finish. The Blues, currently in fourth, are currently level on points with Tottenham but have a game in hand.
Benitez, speaking to the Telegraph, explained the nature of his heated rivalry with Ferguson by saying, “The manager is there and you are close to him on the touchline, so if he wants to fight, you have to fight."
"I don’t like any confrontation but obviously you want to stand up. I don’t have any problem with that.
“I like to concentrate on football issues, that is the main thing, tactically and details about the game.
“In England, sometimes you talk about mind games but, if you have a very good team, you will win the mind games.
“The mind games is just an excuse when you don’t want to talk about the other things.”
Meanwhile, Ferguson hopes his side won't let up despite having sewn up a 13th Premier League title two weeks ago.
"[Nemanja] Vidic came to me and asked could they go to Chester Races next Wednesday and I said without thinking 'yes of course' and then we put all these things together and I was saying 'bloody hell, I hope they don't forget there are games of football to be won'," he said on Saturday.
But he insisted that they still have the responsibility of winning every game for the remainder of the season.
He added: "It is difficult, they have had a fantastic season and they deserve to celebrate as a team. They have had a hard season but they still have to win games."
The match could be the last time that Benitez and Ferguson face one another in the Premier League for some time as the Daily Mail reports that the Spaniard is in talks with Schalke to finalise a move to Germany.