Stoke travel to Sunderland on Monday, with Paolo Di Canio's side without Stephane Sessegnon for the rest of the season after the forward lost his appeal against the red card picked up at Villa.
The Black Cats had secured back-to-back wins over Newcastle and Everton without conceding a goal to ease their relegation fears, but Di Canio labelled the crushing defeat at Villa as "unacceptable".
At the other end of the table, Rafael Benitez's Chelsea are not in action until Sunday's clash with Manchester United at Old Trafford.
On Saturday, Wigan's annual role as the Barclays Premier League escape artists was reprised again as they won 3-2 at West Brom.
Time and again Roberto Martinez's men have ended the season strongly to stay up, but going into Saturday's meeting five points shy of the rest, they looked in trouble.
That situation increased when Shane Long tucked in Markus Rosenberg's cross for the Baggies, but Arouna Kone levelled before the break.
Gareth McAuley put West Brom ahead again five minutes after the restart but Wigan, never-say-die merchants, equalised through James McArthur (58) and won it when Callum McManaman scored with 10 minutes left.
Wigan now have 35 points, three less than Norwich whose dismal 2013 continued as they were beaten 2-1 by Aston Villa.
A 0-0 draw at West Ham leaves Newcastle in bother on 38 points, but being already relegated played into the hands of Reading who went goal crazy at Fulham, winning 4-2.
Tottenham struck a potentially lethal blow in the race for a top-four place
Spurs were struggling to find a way past Southampton at White Hart Lane until the man of the moment, PFA Player of the Year Gareth Bale, unleashed a stinging 20-yard winner to put them temporarily into fourth ahead of Arsenal, with the Gunners taking on QPR in the late game.
Tottenham's place in the top four was soon gone, though, with Theo Walcott's first-minute goal giving Arsenal a 1-0 win over QPR at Loftus Road.
Sunday's Premier League Fixtures
Liverpool vs Everton
Man United vs Chelsea
Monday's Premier League Fixture
Sunderland vs Stoke
Saturday's Premier League Results