The Royals face fellow strugglers QPR on Sunday knowing if either side lose they will become the first team to be relegated to the npower Championship.
However, victory on Saturday would still not be enough to avoid the drop if Aston Villa beat Sunderland on Monday night, which would leave only one place in the bottom three to be filled.
A draw would only stall the seemingly inevitable, with both Reading and QPR set to be relegated if Wigan beat Tottenham, or if Aston Villa avoid defeat against the Black Cats.
QPR manager Harry Redknapp has said his players must bounce straight back to the Premier League next season, having seemingly already accepted the fate which awaits his side.
But Adkins remains positive and is only looking ahead to the fixture with QPR, rather than the possibility of falling out of the top flight.
He said: "The environment we have got here is that everyone is working very, very hard and I have been very positive about that.
"There is a positivity about the place, you could talk about how could there be that positivity with were we sit in the table, but there is and that is important.
"We are not down first of all. What we have got in a group of players who are working very hard and we are looking at one game at a time, that is the way we have gone about it."
Former Southampton boss Adkins believes he has seen a progression in the team since he replaced Brian McDermott at the helm and will be hoping to pick up Reading's sixth league win of the season on Sunday.
"Like everything you are always building towards the future, looking forward in everything you do and the most important thing is look to go out in our next game and win the game of football," he said.
"We have got a great game at the weekend, in front of our supporters at the Madejski Stadium.
"The lads have been working hard during the course of the week on the training ground and we are going to go out looking to get three points.
"We look at the four games I have come in for and from the first game against Arsenal to the last game at Norwich City, taking the results away we are looking at performances and there has been a good improvement from my eyes.
"That has been positive but we need to win games of football and we are very aware of that."
Although coy on whether he would be managing a Royals' side in the Premier League or npower Championship next season, Adkins did admit plenty of preparations are under way.
"I think you will find that with all football clubs," he said.
"Whether they are in the Premier League, Championship, League One, League Two or the Conference - everybody is always looking at what division they could potentially be in next season and the players they might bring in.
"Everyone has got recruitment department now, looking to move players around and bring new players in with fresh impetus and we are no different to every other club."
Adkins will welcome Hal Robson-Kanu back into his squad for the clash with QPR after the winger returned to training earlier in the week.but he will still be without Adam Federici, Hope Akpan and Jimmy Kebe, who are absent through injury.