Arsenal vs Norwich
Arsenal midfielder Tomas Rosicky faces a fitness test on his hamstring and is rated as 50/50. England duo Jack Wilshere (ankle) and Theo Walcott (hip/thigh) are ready to return but centre-back Per Mertesacker serves a one-match suspension, so captain Thomas Vermaelen is set to return to the defence. Midfielder Abou Diaby (knee) is a long-term absentee.
Norwich will assess the fitness of goalkeeper Mark Bunn (groin). Lee Camp is ready to deputise, while winger Anthony Pilkington should be available again after his hamstring injury. England goalkeeper John Ruddy will not yet be risked as he continues his recovery from thigh surgery.
Top scorers (all competitions): Theo Walcott (Arsenal) 18; Luciano Becchio (Norwich) 18
Referee: Mike Jones (Cheshire)
Aston Villa vs Fulham
Aston Villa striker Darren Bent is nearing a return to full fitness but is still short of match sharpness. Manager Paul Lambert is also keeping an eye on the fitness of defender Ciaran Clark following a shoulder injury. Defender Chris Herd, winger Marc Albrighton (both foot) and defender Richard Dunne (groin) remain on the casualty list.
Fulham midfielder Eyong Enoh will undergo a late fitness test after injuring his ankle against Newcastle last weekend. Cottagers boss Martin Jol is already without midfielders Steve Sidwell (suspension), Ashkan Dejagah (ankle) and Mahamadou Diarra (knee). Dejagah will undergo ankle ligament surgery next week, joining Diarra on the sidelines for the remainder of the season.
Top scorers (all competitions): Christian Benteke (Aston Villa) 22; Dimitar Berbatov (Fulham) 13
Referee: Phil Dowd (Staffordshire).
Everton vs QPR
Everton midfielders Marouane Fellaini and Steven Pienaar both return from suspension. Manager David Moyes reported a few unnamed players had niggles but nothing too serious. Full-back Tony Hibbert made his first competitive outing after four months out with a calf problem for the under-21s this week.
QPR are missing striker Bobby Zamora due to suspension. Zamora will begin his three-game ban as a result of being sent off against Wigan last weekend. Shaun Wright-Phillips is out after undergoing ankle surgery but manager Harry Redknapp has otherwise declared a clean bill of health.
Top scorers (all competitions): Marouane Fellaini (Everton) 12; Loic Remy (QPR) 8
Referee: Lee Mason (Lancashire).
Reading vs Liverpool
Jimmy Kebe will miss out for Reading because of a groin problem while fellow midfielder Hope Akpan is a major doubt due to an ankle injury sustained in last Saturday's 2-0 defeat to Southampton. Royals boss Nigel Adkins said Reading have further niggles but no other players are expected to be ruled out.
Forward Raheem Sterling will be absent again for Liverpool as the club continue to manage the teenager's thigh injury. Winger Stewart Downing, who played in last weekend's goalless draw with West Ham despite illness, is now fully recovered. Forward Fabio Borini and midfielder Joe Allen (both shoulder) are sidelined, as is defender Martin Kelly (knee).
Top scorers (all competitions): Nick Blackman (Reading) 14; Luis Suarez (Liverpool) 29
Referee: Mark Clattenburg (Tyne & Wear).
Southampton vs West Ham
Southampton manager Mauricio Pochettino could be without a trio of players after a virus sidelined Luke Shaw, Jason Puncheon and Jay Rodriguez. Other than the three players fighting illness, Pochettino's side has a clean bill of health.
West Ham will have on-loan striker Andy Carroll available after he was ineligible for last weekend's goalless draw against parent club Liverpool. Midfielder Joe Cole (hamstring) and Mark Noble (shoulder) are still sidelined, while defenders Winston Reid (hip) and George McCartney (knee) also remain out.
Top scorers (all competitions): Rickie Lambert (Southampton) 14; Kevin Nolan (West Ham) 6
Referee: Mike Dean (Wirral).
Newcastle vs Sunderland
Newcastle defender Steven Taylor could be fit having missed the draw with Benfica with a knee problem. Midfielder Hatem Ben Arfa has shown no ill-effects following a hamstring problem while full-back Mathieu Debuchy and midfielder Cheick Tiote are working their way back from similar complaints. Defenders Davide Santon (hamstring) and Fabricio Coloccini (back) are expected to miss out.
Sunderland will be without suspended midfielder Craig Gardner but will hope for better news of defender Carlos Cuellar (ankle) and striker Danny Graham (knee), who have trained this week. Frontman Connor Wickham is a doubt with an unspecified knock.
Top scorers (all competitions): Yoan Gouffran (Newcastle) 13; Steven Fletcher (Sunderland) 11
Referee: Howard Webb (S Yorkshire).
Stoke vs Man Utd
Stoke will check on the fitness of midfielder Matthew Etherington (back) and defender Marc Wilson (back/hamstring), with both players forced off in the loss to Aston Villa last weekend. Midfielder Glenn Whelan has trained this week and is fit to return after a back problem.
Ashley Young will be sidelined for Manchester United, he is facing two weeks out with an ankle injury sustained during the defeat to Manchester City. Jonny Evans (hamstring) should be fit while skipper Nemanja Vidic (calf) returns to training. Paul Scholes (knee) is definitely out.
Top scorers (all competitions): Jonathan Walters (Stoke) 9; Robin van Persie (Man Utd) 23
Referee: Jon Moss (W Yorkshire).