Note: Team news will be updated as soon as teams release relevant fitness updates for the weekend's fixtures.
Chelsea vs Manchester United
United midfielder Kagawa picked up a knee injury against Braga on Tuesday and faces four weeks on the sidelines, meaning he will miss Sunday's trip to Chelsea and the following weekend's encounter with Arsenal, plus the return Champions League game with Braga and his country's World Cup qualifier with Oman on November 14.
Chris Smalling has returned to training after a broken metatarsal but Phil Jones (knee) and Anders Lindegaard (thumb) remain sidelined as United look to record their first Premier League win at Stamford Bridge since 2002.
Lampard will be sidelined for at least a fortnight with a calf problem.
He limped out of Tuesday's Champions League defeat at Shakhtar Donetsk with a recurrence of the injury he suffered before the international break and will miss both Sunday's game and the League Cup clash with United as well as a trip to Swansea and the Champions League return against Shakhtar.
John Terry will serve the remainder of his ban in the first three of those games while Marko Marin is back after a minor injury.
Arsenal vs QPR
Full-back Bacary Sagna could return to the Arsenal squad for Saturday's Barclays Premier League clash against QPR after recovering from a broken leg.
England midfielder Jack Wilshere also played for the under-21s earlier in the week and may be on the bench as his rehabilitation from ankle and knee injuries continues.
Midfielder Alex Oxlade-Chamberlain (hip) faces a fitness test, but defender Kieran Gibbs (thigh) and forward Theo Walcott (chest) remain sidelined, along with first-choice goalkeeper Wojciech Szczesny (ankle), midfielder Abou Diaby (thigh) and Czech winger Tomas Rosicky (hamstring).
QPR captain Park Ji-sung is doubtful for the Barclays Premier League clash at Arsenal on Saturday.
The former Manchester United midfielder suffered a knee injury in the 1-1 draw against Everton and has not trained fully all week.
Ryan Nelsen and Armand Traore, who were both substituted during the game, are both available to manager Mark Hughes who is still looking to guide QPR to their first league win this season. Both Fabio (hamstring) and Andrew Johnson (knee) remain sidelined.
Everton vs Liverpool
Everton manager David Moyes is hopeful midfielder Marouane Fellaini and full-back Tony Hibbert will be fit for Sunday's Merseyside derby against Liverpool at Goodison Park.
Fellaini missed last weekend's draw with QPR because of a knee injury while Hibbert has not played for more than a month after sustaining a calf problem.
Midfielder Darron Gibson (thigh) is still sidelined and playmaker Steven Pienaar serves a one-match ban after his controversial sending-off at Loftus Road.
Liverpool boss Brendan Rodgers will continue to monitor the condition of goalkeeper Jose Reina ahead of Sunday's Barclays Premier League derby clash with Everton at Goodison Park.
Reina has been nursing a hamstring problem picked up on international duty with Spain and missed the win over Reading last Saturday and Thursday's Europa League victory against Anzhi Makhachkala, but has been back in training at the Reds' Melwood complex.
Rodgers has no fresh injury concerns, with Martin Kelly (knee), Lucas Leiva (thigh) and Fabio Borini (foot) remaining sidelined.
Manchester City vs Swansea
Champions Manchester City are again without playmaker David Silva and a number of other players for their Barclays Premier League clash with Swansea.
Silva continues to struggle with the hamstring injury which has kept him out for the past two games while defenders Pablo Zabaleta (hamstring) and Maicon (foot), and midfielders Javi Garcia (thigh) and Jack Rodwell (hamstring) are also missing.
Another midfielder, James Milner, also sits out through suspension after his sending-off at West Brom last weekend.
Swansea manager Michael Laudrup has no fresh injury concerns ahead of Saturday's trip to face Manchester City.
The Dane could opt to again start midfielder Michu in attack after the Spaniard claimed his sixth goal of the season when employed as a striker in the win over Wigan, with Danny Graham the alternative.
Pablo Hernandez and in-form Wayne Routledge look set to keep Nathan Dyer on the bench, while Kyle Bartley (thigh) and Neil Taylor (broken ankle) are the only long-term absentees.
Aston Villa vs Norwich City
Aston Villa are facing a potential centre-back injury crisis for the home Barclays Premier League clash with manager Paul Lambert's former club Norwich.
Richard Dunne (groin) is definitely ruled out while Nathan Baker (ankle) and Ciaran Clark (knee) will be assessed later on Friday.
Matt Lowton is on stand-by to switch into the centre with Eric Lichaj in contention to earn a recall as his replacement at right-back as Villa look to improve on a record of one win in 18 league games.
Norwich manager Chris Hughton has no fresh injury concerns for the Barclays Premier League fixture away to Aston Villa on Saturday.
Reserve goalkeeper Mark Bunn is targeting a possible return from injury against Tottenham on Wednesday in the Capital One Cup.
Full-back Steven Whittaker, whose ankle injury has kept him out of senior action all season, could also feature against Spurs after coming through a development outing earlier this week at Reading. Meanwhile, Harry Kane, on loan from Spurs, is on course to return before Christmas following foot surgery.
Wigan vs West Ham
Wigan could be without winger Ryo Miyaichi for Saturday's Barclays Premier League clash against West Ham at the DW Stadium.
The Japan international is suffering from a slight groin problem and is a doubt for the match, where Wigan will bid to end a six-game winless run in the league.
The Latics will again be without winger Albert Crusat (knee) and defender Antolin Alcaraz (groin), with manager Roberto Martinez admitting the Paraguayan centre-back is unlikely to be back much before Christmas.
West Ham boss Sam Allardyce will welcome defender Joey O'Brien back into the squad for Saturday's Barclays Premier League clash at Wigan.
The 26-year-old suffered a hamstring injury during the Hammers' 2-1 win at QPR at the start of the month and his return will ease Allardyce's defensive worries.
Matthew Taylor (calf) and Guy Demel (thigh) could return to first-team action shortly, but Allardyce will have to wait longer for both Ricardo Vaz Te (shoulder) and Jack Collison (knee), whose injuries are more long term.
Stoke vs Sunderland
Stoke boss Tony Pulis could be set to welcome back midfielder Glenn Whelan into his side for Saturday's Barclays Premier League match against Sunderland.
Whelan returned to training on Thursday after recovering from the hamstring problem he picked up in the 0-0 draw at Liverpool earlier this month.
Pulis has no other injury worries ahead of the clash at the Britannia but striker Cameron Jerome could be set to leave the club on loan before the weekend after npower Championship side Blackburn were strongly linked with a move for the player.
Sunderland skipper Lee Cattermole will return to the squad for Saturday's Barclays Premier League trip to Stoke.
The 24-year-old midfielder has missed the last three games through suspension after being sent-off for the seventh time in his career during the 2-0 Capital One Cup third-round victory at MK Dons on September 25.
Full-back Phil Bardsley has a chance of being involved for the first time this season after making the bench for Sunday's derby draw with Newcastle following his recovery from an ankle injury, but central defender Titus Bramble (hip flexor) remains a doubt and Wes Brown (knee) is still out.
Reading vs Fulham
Reading forward Noel Hunt could make his comeback from a heel injury in Saturday's Barclays Premier League game against Fulham.
Royals boss Brian McDermott must decide whether to stick with Alex McCarthy or recall Adam Federici in goal.
Midfielder Jem Karacan is absent with a knee injury.
Fulham winger Damien Duff is available for Saturday's Barclays Premier League clash at Reading after recovering from an illness.
Midfielder Simon Davies is still sidelined with a hip problem and misses out.
Otherwise boss Martin Jol has a fully fit squad to select from.
Southampton vs Tottenham
Southampton will again be without record signing Gaston Ramirez for Sunday's Barclays Premier League game against Tottenham as he continues his recovery from a thigh injury.
Defender Frazer Richardson (groin) and midfielder Jack Cork (knee) are both out, but Tadanari Lee has recovered from his elbow injury and could feature.
Young defender Luke Shaw has overcome his illness and may make his Barclays Premier League debut.
Tottenham's Gareth Bale will return from paternity leave to face former club Southampton on Sunday.
The Wales international missed the games with Chelsea and Maribor after the birth of his first child and will be joined in the squad by Brad Friedel, who also did not travel to Slovenia for Thursday's Europa League tie.
Emmanuel Adebayor could returns after back pain and be joined at St Mary's by Mousa Dembele, who has recently struggled with a hip complaint. Michael Dawson (illness) will be assessed, while Scott Parker (Achilles), Benoit Assou-Ekotto and Younes Kaboul (both knee) are all sidelined.
Newcastle vs West Brom
Newcastle midfielder Cheick Tiote will miss Sunday's Barclays Premier League clash with West Brom as he starts a three-match ban.
The Ivory Coast international is suspended after being sent off during the first half of last weekend's 1-1 derby draw at Sunderland.
However, manager Alan Pardew is likely to restore most of the men he left out of the starting line-up for last night's 1-0 Europa League victory over Club Brugge with Tim Krul, Danny Simpson, Fabricio Coloccini, Mike Williamson, Yohan Cabaye, Jonas Gutierrez, Hatem Ben Arfa, Shola Ameobi and Demba Ba all rested.
West Brom will check on the fitness of midfielder Claudio Yacob before finalising their side for Sunday's Barclays Premier League clash with Newcastle at St James' Park.
The Argentina international suffered a hamstring injury during last weekend's home reversal against Manchester City.
Skipper Chris Brunt (hamstring) and right-back Billy Jones (knee) have resumed training and could be in contention.