Although Ferguson refuses to give up all hope, even he concedes it would take something stupid for his Manchester United side to secure top spot now.
If City beat QPR at the Etihad Stadium, it would complete an achievement worth recognising for Blues boss Roberto Mancini, one that even Ferguson accepts goes far beyond merely assembling a squad at vast cost.
"To win the league is not easy," said Ferguson.
"Many people underestimate how difficult it is to win the league.
"Of course, Roberto Mancini has had a big financial advantage over everyone but you have still got to put a team on the pitch and pick the right players.
"The manager must take the most credit if you win the league over here because when you have squads of players trying to orchestrate the harmony in the place is very important.
"Making everyone feel they have played their part is not easy in the modern game.
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"To win the league is a massive step forward for Mancini."
The City boss clearly has no managed to maintain stability all season as the erratic behaviour of Mario Balotelli and Carlos Tevez prove.
None of that matters now, though, with just one game to negotiate and Ferguson crossing his fingers that United old-boy and former City boss Mark Hughes can do him a favour as his QPR side fight for their Premier League futures.
QPR, who conceded six at Chelsea a fortnight ago and have collected just two points from their last 12 Premier League away games, have little chance of becoming only the second team to deny City a home win this season.
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