Birmingham Heartlands Hospital confirmed on Monday afternoon the former England striker has been released, with the 57-year-old having recovered well from successful surgery.
A hospital spokesperson said: "Trevor Francis was discharged from Birmingham Heartlands Hospital this afternoon [Monday]."
The news comes as welcome relief, not just to Francis' family but to the footballing world, who have shown their support over the weekend.
It also comes on the same day that Bolton midfielder Fabrice Muamba has been discharged from the London Chest Hospital after his cardiac arrest on the pitch during an FA Cup tie with Tottenham at White Hart Lane on March 17.
Francis earned legendary status with Birmingham, the club where he starred between 1970 and 1979 before becoming Britain's first £1million player when he joined Nottingham Forest.
He went on to score the winning goal for Forest in the 1979 European Cup final against Malmo, subsequently helping the team reach the 1980 final against Hamburg although he missed the victory through injury.
And current Forest chairman Frank Clark, who played alongside Francis for the Reds in their 1979 triumph, has wished his former team-mate well.
"I was shocked to hear the news that Trevor had been taken ill," Clark told the club's official website.
"On behalf of everyone at Nottingham Forest I would like to wish Trevor a full and speedy recovery."
Gary Lineker added his delight that both Francis and Muamba had been released.
Using twitter, he wrote: "I see Fabrice Muamba has been released from hospital. How good is that? #miraculous. Trevor Francis also discharged from hospital after a suspected heart attack. Good news all round."
Francis left Forest in 1981 and enjoyed spells with Manchester City, Sampdoria, Atalanta and Rangers.
And Rangers manager Ally McCoist told the Glasgow club's official website on Sunday: "I had the pleasure of playing with Trevor later in his career at Ibrox and I know he enjoyed his time in Scotland.
"It was a shock to hear of his heart attack but he is a fighter and I hope he can make a quick and complete recovery.
"On behalf of everyone at Rangers Football Club I wish Trevor and his family well at this difficult time."
Francis won 52 England caps and represented his country at the 1982 World Cup, later enjoying player/manager stints with QPR and Sheffield Wednesday.
The Plymouth-born forward returned to Birmingham as manager in 1996 and led the club to three play-off semi-finals as well as the 2001 League Cup final, which they lost to Liverpool on penalties.
After leaving St Andrew's in 2001, Francis had a two-year spell as manager of Crystal Palace and has since worked extensively as a television pundit.