The Uruguay international was slapped with an eight-match ban after the FA found him guilty for racially abusing United defender Patrice Evra on October, and knows that he will be in for a hot reception when his team travels to Manchester for their showdown against the Red Devils.
The former Ajax man is unbothered by this, however, and has said that he will use the jeers as a source of motivation to do better during the match.
Suarez, speaking on Radio Sport 890, said: "I know against Man United it is going to be tense because I'm going to face Evra. But I'm used to having fans whistle at me. I hope nothing unusual happens. I'll have to forget what happened for that moment.
"I do know Man United fans are going to try to make me feel uncomfortable.
"But I have to tell them - they are going to spur me on if they whistle at me."
The 25-year-old went on to express his dismay on how the dispute between him and Evra should have simply ended on the pitch, instead of turning into a whole saga.
"I was not depressed at all. I knew what I did and there is a kind of football law that says 'what happens on the pitch, stays on the pitch and that's the end of the story'."