Stoke lost the FA Cup final to Roberto Mancini's side in May but Huth has placed the emphasis on getting three points at the Etihad Stadium rather than settling a score for the Wembley defeat.
The German, who scored in the weekend's 2-1 victory at Wolves which extended his side's winning run in the league to four games, has predicted a difficult time against a City side leading the table after winning their past 15 home matches.
Huth said of the FA Cup final defeat: "It doesn't mean anything really, that happened seven or eight months ago.
"They won the game fair and square and we have moved on from that.
"We don't want any sort of revenge, we are just concerned about getting the results we want, for us, and not worrying about whether it impacts the other side or not."
Huth has been enthused by City's run in the league and also progress to the last 32 of the Europa League.
"It's been a great few weeks for us in terms of picking up points and progressing in Europe, but we know that Wednesday night will be incredibly tough for us," he told the club website, www.stokecityfc.com.
"They are one of the best sides in the country, if not Europe, so we are under absolutely no illusions as to the size of the task in front of us because they are going so well at the moment.
"We have had a few good results though so we can take that into the game with us; but even with that we know it will be an incredibly tough evening for us. We will give it our best shot though."
Stoke could be without both Ryan Shawcross and Glenn Whelan for the difficult trip to the Etihad Stadium on Wednesday.
Defender Shawcross is definitely out as he is suspended after picking up his fifth yellow card in the win at Wolves.
Midfielder Whelan is a doubt with a calf muscle injury suffered at Molineux and full-back Andy Wilkinson is likely to miss out again with a back problem.