The former Gunners captain completed his long awaited move back to Barcelona in January after eight years at the club.
And Wilshere, who is tipped to be the future replacement for Fabregas, believes the Spaniard could return to the Emirates one day.
"I still speak to Cesc quite a lot. He texted me the other day after my operation," the young Englishman told The London Evening Standard.
"It [the link with Barcelona] had been going on with Cesc for a couple of years, so I guess we always knew he would go at some point.
"Especially this year, Cesc wanted to leave and when a player wants to leave, the boss did the right thing.
"He'd been great for us and was one of our best players for the last six years.
"If you look at him now, he's flying. It'd be nice if he came back one day - the door is always open for him because of what he did at Arsenal.
"You'd almost say he's an Arsenal legend now and I think the fans would welcome him back as well."
Fabregas missed Barcelona's 1-0 weekend win over Sporting Gijon with a hamstring injury and was not called up to the Spain squad for their forthcoming Euro 2012 qualifiers against Czech Republic and Scotland in Group I.
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