Spurs' poor scoring record in the league cost them a place in this year's Champions League, with Defoe, Roman Pavlyuchenko and Peter Crouch finding the net just 18 times last season.
Tottenham boss Harry Redknapp sought to remedy that problem by replacing Crouch with Adebayor and the move paid immediate dividends when the Togolese marksman scored on his debut in Spurs' 2-0 win at Wolves on Saturday.
Defoe, who netted just four Barclays Premier League goals last term, was also on the scoresheet at Molineux with a clinical finish from inside the box after losing his marker.
The England international now hopes he can build up a good relationship with Adebayor to help him keep scoring and also revealed that he was desperate for the former Arsenal man to join when he was first linked with the London club this summer.
"He is brilliant. I was looking forward to it (playing with him) even before he came," Defoe told Spurs TV Online.
"There was a lot of speculation that he was coming and I just thought to myself 'please let it happen' because he's a great player.
"He's quick, he can head it, he is strong and he is a good finisher.
"He can do everything. Him being there freed me up a bit because it allowed me to drop deep, get on the ball and beat players so it was good."
Defoe had to wait until March to score his first league goal of last season after being dogged by loss of form and fitness, but he is sure this season will be a different story.
"I have a had a good pre-season. Last year I didn't get one so that made it difficult," he said.
"If you put the work in pre-season you will have a good season. I just want to keep working hard and I know I will get more goals."
After two heavy defeats to Manchester United and neighbours City, Saturday's win at Wolves was exactly what Redknapp and his squad needed.
The long-running transfer saga concerning Luka Modric and Chelsea also disrupted the squad's early-season form, but club captain Ledley King thinks their troubled start is now behind them.
"All the deals have been done. We have our team now and I suppose it's a case of just getting on with it," King said.
"There is no chance to wonder if anyone else is coming here or if anyone is leaving now. We have our squad now and we are settled. I think that showed on Saturday."
The club now face a testing spell in which they will play PAOK Salonika, Liverpool and Stoke within a six-day period.
Matters have been made worse by an Achilles injury to Michael Dawson which could reportedly rule him out for two months.
There has been no official confirmation of how long the defender expects to be out for, but the injury is understood to be a long-term one.
Should he miss the next two months, it will be a cruel blow for the England man as he spent three months out with a similar injury last term.
His loss will also be felt by the team. William Gallas is 10 days away from full fitness with a calf complaint, Vedran Corluka missed Saturday's win through injury and King's chronic knee problems mean he will only be able to play one of the three upcoming fixtures.
King, who has been told by Redknapp that he needs to play 20 games this year to earn a new contract, was playing his first game of the season on Saturday after having an operation on his knee this summer.
He was relieved to get through Saturday's win at Molineux unscathed.
"I came through okay," said the 30-year-old.
"I just cramped up at the end a bit but that's normal."