Dembele's ankle injury has proved troublesome, keeping him out for more than seven weeks, and his return would add much-needed firepower to the struggling Cottagers' ranks.
Goalkeeper David Stockdale will make his first appearance since August as Mark Schwarzer departs for Australia's Asian Cup campaign, while Matthew Briggs (calf), Bobby Zamora (leg) and Philippe Senderos (Achilles) remain out.
Baggies boss Roberto di Matteo has more defensive problems to contend with.
Pablo Ibanez (ankle) and Stephen Reid (knee) were both forced off during Saturday's disappointing defeat to Manchester United and Di Matteo does not expect either man to be fit.
At least Gonzalo Jara is back after a one-match ban for the Baggies, who have now lost four matches on the trot.
Fulham (from): Stockdale, Kelly, Salcido, Hughes, Baird, Hangeland, Halliche, Duff, Dempsey, Murphy, Davies, Gera, Etuhu, A Johnson, E Johnson, Pantsil, Dembele, Kamara, Greening, Dikgacoi, Etheridge.
West Brom (from): Carson, Cech, Ibanez, Morrison, Jara, Barnes, Brunt, Reid, Myhill, Fortune, Dorrans, Shorey, Thomas, Mulumbu, Zuiverloon, Meite, Odemwingie, Fortune, Tchoyi, Scharner, Thomas, Cox, Downing, Sawyers, Allsopp, Miller, Kiely.