Ever the eccentric, the outspoken Eagles boss kicks off a two-match touchline ban at Old Trafford for comments made on the opening day of the season.
Holloway was charged with two separate counts by the Football Association for comments made about officials following the 1-0 defeat by Tottenham - charges he chose not to contest.
It means the Palace boss will also be stuck in the stands for next weekend's clash with Swansea after a lack of discipline he admits he "should have grown out of" by now.
"I am disappointed in myself," Holloway said. "I am disappointed when I don't get what I want and with how I behave sometimes.
"I've got to learn how not to do that, but I can't help being passionate.
"It is only a touchline ban, they can hardly hear me standing there anyway.
"I'll be able to do my job before the game, be at the hotel with them before the game, in the dressing room and in there at half-time and after the game.
"It is only a touchline ban, but the rules being what they are I was deemed unfit to be on the bench, in that area, and that hurts me more than you'll ever know.
"It has cost me an awful lot of money and an awful lot of pride, really. I would love to have been stood on the sidelines."
The match, though, will be a welcome return to on-field action after a hectic few weeks.
After collecting a first win of the season against Sunderland, Holloway went onto bring in six players in a flurry of late transfer activity.
Jack Hunt, signed from Huddersfield, is one of that sextet but already faces a lengthy spell on the sidelines, as does academy graduate Jonny Williams, who sustained injuries over the international break.
"The severity is pretty bad for us," Holloway said.
"We've just had a broken leg on Jack. In a funny way sometimes bones mend quicker and easier than ligaments.
"If there is any good news for him, it is a clean break. There is no ligament damage.
"It was a sort of freakish accident, where he planted his foot and everybody heard a crack so that's not good.
"Then Jonny Williams gets booted in this international game, which I am not happy about. It is so cowardly it is unbelievable.
"We're going to be missing him for God knows how many months. With Jack it will be weeks and with Jonny it might be months [due to ankle ligament damage].
"Jack will be in a pot and when that comes off it might be six weeks, two or three months. Who knows?
"It is a big blow for Jack but I think it will be easier for him to fix than Jonny's."