Premier League LIVE coverage will begin at 8.45PM HKT/6.15PM IST! Do join us then as we cover the game between Manchester United and Stoke!
Sergio Aguero's second-half winner in the Manchester derby on Monday night leaves United 12 points clear of City at the top of the table.
Against Stoke they want to brush off any hint of a blip and, with City not in league action until Wednesday, have a chance to reopen the gap between themselves and their local rivals.
Victory for Sir Alex Ferguson's side will move them to within seven points of the championship.
United face a Stoke side just three points clear of the bottom three, with one win since the turn of the year.
Usually formidable at home, the Potters have not won at the Britannia Stadium since February, and the prospect of relegation is a real possibility.
"It's a game that we are looking forward to," said Stoke boss Tony Pulis.
"This is why you want to be in the Premier League. We have given them good games here before."
He added "The time has come for us to win a couple of games and put this right. Then we will look at what went wrong at the end of the season."
Newcastle vs Sunderland (Starting XIs will be published 30 minutes before kick-off)
Newcastle: Krul; Debuchy, S.Taylor, Yanga-Mbiwa, Gutierrez; Tiote, Cabaye; Marveaux, Sissoko, Gouffran; Cisse
Subs: Elliot, Perch, Haidara, Anita, Ben Arfa, Campbell, Shola Ameobi
Sunderland: Mignolet; Bardsley, Cuellar, O'Shea (c), Rose; Johnson, N'Diaye, Larsson, McClean; Sessegnon; Graham
Subs: Westwood, Kilgallon, Colback, Vaughan, Mangane, Mandron, Laidler
Stoke vs Manchester United Starting XIs
Stoke: Begovic; Cameron, Shawcross, Huth, Wilkinson; Shotton, Whelan, Nzonzi, Adam, Walters; Jones
Subs: Sorensen, Palacios, Owen, Whitehead, Kightly, Crouch, Jerome.
Manchester United: De Gea; Vidic, Evra, Jones, Ferdinand; Kagawa, Carrick, Valencia; Rooney, Hernandez, Van Persie
Subs: Lindegaard, Evans, Giggs, Smalling, Welbeck, Cleverley, Buttner
Also on Sunday, St James' Park hosts one of the biggest Tyne-Wear derbies in recent years as Paolo Di Canio's Sunderland make the 10-mile trip to Newcastle.
The Magpies eased their relegation fears with a late win over Fulham last time out, but their north-east rivals are only out of the drop zone on goal difference, with Wigan immediately below them carrying a game in hand.
"We need three points, but the most important thing is for red and white scarves to be celebrating," said new Black Cats boss Di Canio.
"Then it would be a day to remember for many years."
Sunderland have not defeated Newcastle on Tyneside for over 12 years and Di Canio added: "The last time we won a derby away was in November 2000 with Niall Quinn and Don Hutchison. That is too long."
Sunday's Premier League Fixtures
Newcastle vs Sunderland
Stoke vs Man United
Saturday's Premier League Results