The players were banned by the K-League and KFA following an investigation dating back to the summer of 2011.
However, around half the players involved have been offered hope of one day returning to football after coming forward during a voluntary reporting period.
A FIFA statement today confirmed: "All 41 players have been sanctioned with a lifetime ban from all football activity by the K-League and the Korea Football Association's disciplinary committees. The FIFA Disciplinary Committee has extended the sanctions to have worldwide effect.
"However, 21 players who turned themselves in during the voluntary reporting period, expressing their grave regret about their involvement in match-fixing, have been offered the possibility of returning to football after a probation period of between two and five years. This includes carrying out periods of community service ranging from 200 to 500 hours."
The voluntary probation period would require a player to inform the K-League of his wish to return to football, and then commit himself to a community service involving coaching for local clubs, support for disability football or support for anti-match-fixing activities.
Ten other players saw K-League and KFA sanctions applied worldwide by FIFA last June after their involvement in match-fixing.