By ESPNSTAR.com staff
Spurs will make the short trip to the Emirates Stadium when they take on the Gunners in one of the most eagerly-anticipated fixtures of the Barclays Premier League.
Clashes between Arsenal and Spurs have always been hotly contested, and Saturday's derby clash will take on extra significance with the Lilywhites looking increasingly likely to pip the struggling Gunners as the dominant force in North London.
Vermaelen, who moved to Arsenal in 2009, recognises the North London derby is no ordinary fixture and claims that a win for his side will provide a huge moral boost and could help kick-start their spluttering season.
"This isn't a normal game - it's a special one," the 27-year-old was quoted as saying by the official Arsenal website.
"Practically, we need to get three points on the board, but I think it would give both the fans and the team a massive boost if we won.
"Last season we came back from 2-0 down, working really hard for a memorable turnaround.
"We want to create the same impetus this time and it's a big opportunity to do so.
"If you look at the league table, we're not too far behind third and fourth places.
"Nothing is lost yet - a win against Spurs would be a big step."
The Belgian international also believes that the rivalry between Arsenal and Spurs reach a more intense level than other rivalries.
"Ajax always had a big rivalry with Feyenoord, which was quite similar, but I think it's even more pronounced here," Vermaelen added.
"The level is higher, and it just feels like a step up.
"This is more intense and you can feel that in the atmosphere in the stadium whenever we play Spurs. Without fail, it's unbelievable."
Arsenal are currently eighth in the table on 16 points and could leapfrog Spurs (17 points) in the table with a victory.