The 30-year-old signed a pay-as-you-play deal with the Rio de Janeiro club in August in a bid to recover from surgery on his Achilles tendon, but his long-term future was cast into serious doubt when he skipped three training sessions to activate a release clause in his contract.
Adriano quickly pre-empted his boyhood club's decision to revoke the deal by issuing a statement expressing his desire to avoid playing football until next year, swerving the opportunity to discuss his decision with director of sport Zinho, who was left with no choice but to rescind the contract.
Nevertheless, the former Brazil international extended a generous invitation to his compatriot, intimating he could eventually return to the Engenhao should he overcome his current problems.
Zinho told flamengo.com.br: "Adriano will play no further part for Flamengo, those are his own words.
"His contract will be rescinded.
"I wanted Adriano here with me to talk to you (the press).
"I wanted to speak with him personally on Friday about why he came to this decision, but he was very upset by problems he's having outside of football.
"His first three absences (from training) gave Flamengo the right to terminate the contract, but we took a humane approach to help him recover, ignoring the rules.
"All his doctors, trainers and the players want the best for him, but he has to want it first.
"It makes me sad because I think he is throwing away a great opportunity.
"If he recovers maybe he could be a professional footballer again, and I will keep talking to him as he recovers.
"As director of football here, he has my support."
Flamengo club president Patricia Amorim also insisted the club would do everything they could to support Adriano, who scored over 100 goals in Serie A and the Campeonato Brasiliero as well as 27 goals in 48 appearances for Brazil, and that the "doors of the club are never closed".
"If, one day, he is in good enough condition to play, and proves he is well then we could be interested as all good footballers interest us," she told Brazilian newspaper Terra.
"The doors of the club are never closed, the rescinded contract was only signed in August and I remember that the fans wanted this deal to happen too.
"At the moment, he's not the player for us, but he was the star of the team when we won the championship, and he knows how we operate here.
"We have given him our love, affection and commitment but he has not repaid us.
"We are always ready to help him, but he knows that he cannot play in his current condition."