The move will see national teams having just a two-day break between matches in World Cup and European Championship double-headers, in what is being dubbed The Week of Football.
Teams will play either Thursdays and Sundays, Fridays and Mondays, or Saturdays and Tuesdays. Most double-headers are currently being played on Fridays and Tuesdays - leaving the weekends without football.
UEFA general secretary Gianni Infantino told the Leaders in Football conference in London: "You can play every three days - it's what happening in club football all year long so that's not a problem.
"This has been unanimously supported by all 53 national associations.
"If we leave the weekend to other sports then in the medium and long-term it will be damaging."