Ronaldinho's career seemed to have stagnated at AC Milan, the 31-year-old looking overweight and disinterested, in complete contrast to the vibrant youngster who thrilled crowds at Paris St Germain and Barcelona.
He left Europe and returned to South America with Flamengo in January and has enjoyed a return to prominence with 15 goals in the club's Campeonato Brasileiro title challenge.
Ronaldinho has made just one appearance for the Selecao since being left out of the squad for the 2010 World Cup - a 1-0 defeat to Argentina last year - but Menezes is expecting big things against the Africans as his side attempt to bounce back from a Copa America quarter-final exit and a 3-2 defeat to Germany in another friendly.
He said: "Ronaldinho is a world champion with the Brazil team and after his return to the country he has re-adjusted and he is playing very well.
"He is becoming one of the best players of the season and what has been successful with Flamengo can also help the national team."
Menezes will be without AC Milan playmaker Robinho at Craven Cottage, the home of Fulham, but can call on his club team-mate Alexandre Pato, Porto striker Hulk and Santos star Neymar to occupy the forward positions.
Ghana have their own injury worries with key striker Asamoah Gyan set to miss out with a thigh strain sustained in Friday's African Nations Cup qualifying win over Swaziland.
The Sunderland man, who has looked woefully short of form and fitness for the Wearsiders this season, was disappointed to have missed out on such a glamorous fixture.
He told www.ghanaweb.com: "I would have really wished to feature in this one but I totally understand what the medics are saying.
"It's fine by me and I will cheer the guys on."