Mourinho, who introduced himself as 'The Special One' on his arrival in English football in June 2004, and Wenger cross swords for the 11th time at Stamford Bridge on Saturday in a contest which could have a significant say on the destination of the title, with Liverpool and Manchester City also in contention.
The Portuguese, who has continually played down Chelsea's title chances, described Wenger as a "specialist in failure" after the Frenchman commented that anyone ruling themselves out of the title race was doing so out of a fear of falling short.
The Chelsea boss, who was referring to Arsenal's eight-year trophy drought, afterwards felt he was portrayed as the villain when he believed it was Wenger who resumed the verbal sparring prevalent during the Portuguese's first spell.
Mourinho's 'bad guy' image was given further credence when he was charged by the Football Association this week for improper conduct in relation to his dismissal by referee Chris Foy towards the end of last Saturday's controversial loss at Aston Villa.
"Look, you see the charges from the last match, and you see that I'm different than anyone else," said Mourinho, whose opposite number Paul Lambert was not charged despite also encroaching on the pitch.
"In the eyes of people, I am different. That, I think, is obvious.
"It's obvious there's a measure for some, there is a measure for me.
"There is a way where I can feel the differences, all the time."
The Portuguese will contest the charge, which could see him hit with a £10,000 fine.
He said: "It can be £1. It's the principle."
Mourinho held his counsel on his full thoughts on Foy's performance, yet his plea for the official not to be allowed to referee Chelsea in future was an indication of his anger, which is still simmering.
He added: "Even after Saturday, I keep saying that English referees are very, very good and I have complete trust in them. Even after Saturday."
Mourinho, who has never lost in 10 previous matches with Wenger and in 75 Premier League matches at Stamford Bridge, stopped short of a glowing tribute to the Arsenal boss on the eve of his landmark game.
"There are many ways of paying tribute," Mourinho said.
"For me to pay tribute is to say that he's in a position where everybody would like to be.
"I love my career and the experiences I've had in my career, but he's in a position where everybody would love to be."
Mourinho insisted he was not delivering a backhanded compliment.
"It's a big compliment," he said.
Mourinho is adamant he has no enemies in football, but that few of his managerial colleagues are friends.
"Louis van Gaal is my friend," Mourinho said.
"I worked for him for so long. Other managers you know them, you shake hands, two minutes. Friends? I have a different concept of friends.
"Enemy? No-one. Not a single one."
Mourinho believes it is his duty as home manager to give Wenger a cordial welcome.
"I always go to the opponent's manager. Always," he said.
"It's the right thing to do. Never, never, never in my career, playing a match at home, did I not go to say hello to the opponent's manager."
The renewal of hostilities has coincided with an Arsenal renaissance - they are FA Cup favourites after reaching the semi-finals - and Mourinho believes Wenger's men are performing well this term.
"This season they are better than last season," he said.
"Last season, in this moment, they were struggling to finish top four. This season they are safe in a top-four position and in condition to fight for the title."
The Portuguese believes it is not possible to compare Wenger's current side with the previous Arsenal team he faced.
"The team I met when I came to England in 2004 had everything to be admired," he said.
"There is only one Thierry Henry, only one Patrick Vieira, Dennis Bergkamp, Tony Adams, Sol Campbell, Robert Pires and there is only one team with all of them together.
"There is only one Chelsea with (John) Terry, (Frank) Lampard, (Didier) Drogba, Petr Cech, (Claude) Makelele, (Arjen) Robben, (William) Gallas.
"There is not a second one. You have to try to build a second one, but that is only one."