Along with Willian and Ramires, Mourinho was sent off by referee Chris Foy during a feisty encounter which Chelsea lost 1-0 in a blow to their Barclays Premier League title chances.
Mourinho called for the Premier League to consider not appointing Foy for Chelsea matches in future.
Asked if he had spoken to Ramires about the challenge on Karim El Ahmadi, the Portuguese said: "Don't you have other things to ask about that game more important than Ramires' tackle on minute 92?
"You think that in that game the most important thing was Ramires' tackle in minute 92?
"I don't want to answer, because I feel that what happened on minute 92 was a consequence of the other 92 minutes that we played before that.
"I'm sorry if I'm wrong or if you don't agree with me, but I think if you want to ask you should ask about what made that tackle happen.
"But that's just my opinion."
Mourinho's dismissal was his second of the season.
He was fined £8,000 by the Football Association following his touchline dismissal against Cardiff in October.
He declined to elaborate on the events in the previous 92 minutes of action at Villa Park.
Asked specifically what he was referring to, he said: "Everything that happened. I bring the game into disrepute. I cannot."
Earlier, Mourinho was asked if he expects a reaction from his players following the loss. The Portuguese answered a different question.
"We cannot have a reaction to Villa Park, because if we have reaction we bring the game into disrepute," he said.
"We just close our mouth and we keep going."
Ramires and Willian are free to play in European competition, but left-back Ashley Cole (knee) missed training on Monday morning and is expected to miss out.
David Luiz was present after missing recent fixtures with a groin injury and could come into central midfield in place of Nemanja Matic, who is unavailable after playing for Benfica earlier in the tournament. Mohammed Salah is also ineligible, having played for Basle.
Mourinho was happy to discuss more freely the Galatasaray game, which sees Didier Drogba return to Stamford Bridge, where the striker spent eight years as a Blue, scoring 157 goals in 341 appearances including the decisive penalty in the 2012 European Cup win.
The match also sees Mourinho's predecessor as Inter Milan boss return to English football.
Former Manchester City manager Roberto Mancini had two hours earlier spoken of his willingness to go to dinner with Mourinho if his Gala side won Tuesday's match.
Asked whether he would be happy to have a post-match meal with Mancini, Mourinho said: "No, because I have no interest. After the match I don't do things because I win or because I lose.
"After matches what I have in my mind to do, I do. It doesn't matter if I win or if I lose.
"And in my plans after the game (on Tuesday), I don't have a meal with somebody that has the same job as I have and this is the only thing we have in common. The fact we both are football managers. Nothing else."
Drogba, who is now 36, returns almost two years after his magical moment in Munich which left an indelible mark on the hearts and minds of Chelsea supporters.
"Undoubtedly, he's one of the most important players in the history of this club," Mourinho said.
"All Chelsea supporters, we agree with that. We don't say the most important one because it's not fair on other people.
"Is he the same player at 36 than he was at 26? I think nobody is, but he's one of the best strikers in the world, that's for sure."
Mourinho believes Drogba returning to Chelsea in future, as a player or as a coach, is a possibility.
"(Tuesday) is a big game and I don't think it's the right moment to speak about it," Mourinho said.
"He's a Galatasaray player. We know he's a free agent. We know he finishes his contract at the end of the season, but we know it's not the right moment.
"I think it has to happen one day. When, I don't know. As a player, as a coach, as an ambassador, next year, in four, five years, in 10 years, I don't know.
"But when a person represents so much to a club and when a club represents so much to a person, and that's the case, I think he has to be back one day."
Defender Gary Cahill is to be tasked, along with captain John Terry, with keeping their former team-mate Drogba quiet.
"He's a fantastic player, so playing against him will be tough," Cahill said.
"Emotionally, it'll be strange for him, I'd have thought, but we're focused not on one individual player but the team and on trying to get a good result."
The tie is finely poised at 1-1 following the first leg in Istanbul and Mourinho is uncertain what will happen.
"Everything is there, balanced," he added. "Normally the same kind of match (as Istanbul) with the result that I believe goes till the end."