Pulis fielded a near full-strength side in last Saturday's 2-0 win at West Brom to secure a fourth win in nine matches in charge since succeeding Ian Holloway as boss.
The triumph was in contrast to relegation rivals West Ham, who lost 5-0 at Nottingham Forest in the FA Cup and 6-0 at Manchester City in the Capital One Cup semi-final second leg.
The Hammers' two highs of the season have come at White Hart Lane in the Premier League - they have won once in 13 league games since beating Spurs 3-0 on October 6 - and League Cup, and Palace will aim to emulate the success on Saturday.
Pulis refused to criticise managers who got their comeuppance after fielding weakened teams in the FA Cup, but knows the importance of momentum.
He said: "Winning is everything in sport, especially professional football. You win games and everything is different.
"We've got ourselves a little bit more organised. They (the players) know what I want from them week-in, week-out. That's been the difference."
The Eagles have been revived by Pulis and are two points ahead of West Ham entering this weekend's fixtures.
Three of Palace's wins in the last 10 games - including under caretaker Keith Millen at Hull on the day Pulis' appointment was confirmed - have come away from home.
"Watching the team win away from home gives you confidence," added Pulis, whose side also won at Aston Villa.
"Although you need to win your home games, we have the same amount of away games coming up.
"To be able to go into those games knowing you can win games away from home is important."
Pulis, though, knows defeating a Tottenham side left reeling by FA Cup elimination by North London rivals Arsenal will be a stern challenge for his side.
"If you're looking at it from outside, you'd expect Tottenham to win the game and rightly so," he added.
"How much money they've spent, the wages, the facilities and how established they've been in top-flight football for a long time.
"It's going to be a very difficult 90 minutes, but we go there with great hope.
"We'll work hard and we'll give it the best shot we can."
In Marouane Chamakh, a striker much derided after struggling at Arsenal and West Ham, and Dwight Gayle, a £6million arrival from Peterborough, Pulis believes Palace have match-winners at his disposal.
The pair have netted a combined six goals in the last eight games, four for Chamakh.
Pulis, who could have Cameron Jerome available following a knee injury, added: "Gayle is a young lad and has come to the football club with a massive weight on his shoulders, £6million. It's very important we protect him, we look after him.
"Chamakh I think has been absolutely outstanding since I've come in. He's a really good player.
"What we've got to do with him is tie him down and make sure he works within the structure of the team.
"If he does that, he'll be very, very important for us, because he has got that little bit of quality that everyone looks for."