Former Bayern Munich and Germany goalkeeper Oliver Kahn and back-to-back double-winning coach Felix Magath have both recently given their backing to a new league being formed in which all of Europe's top clubs would play together.
That would ruin domestic football, according to Seifert, who has sung the praises of the Bundesliga.
"Ideas like these are ridiculous," he told Germany's Bild newspaper. "If a European league were introduced, then the Bundesliga would collapse, and so too would other European leagues.
"We had an average of 43,000 spectators coming to our games last year, and all the important TV programmes recorded increased viewing figures.
"And all that happened in 2012/13, which was probably one of the most boring in Bundesliga history."
Bayern marched to the title with ease last term, taking away some of the competitiveness of a league which is renowned for being one of the tightest and unpredictable in Europe.
In 2007, Stuttgart were surprise Bundesliga winners, while in 2009 it was the turn of Wolfsburg to win the league at the first attempt and few had Borussia Dortmund down as serious candidates in 2011.
This season, Bayer Leverkusen and Borussia Monchengladbach have both moved into the frame, although Bayern continue to lead the way and appear on course for a second straight title.