A draw with the Republic of Ireland in Cologne will guarantee their spot in Brazil next summer and Low is determined to progress as Group C winners.
"We're greedy, we want to win the game before a home crowd and secure our qualification," Low said.
"I have fond memories of the compact Cologne stadium and we want to qualify as group winners without questions or discussions. I have a good feeling about this game."
Germany, who sit five points clear at the summit of Group C, thrashed Ireland 6-1 in Dublin last October and the underdogs are currently being coached by caretaker manager Noel King following the resignation of Giovanni Trapattoni.
"The Irish are defensively compact and play with a physical presence. It's in their nature, they defend incredibly well and get back quickly," Low said.
"It doesn't matter which coach is sitting on the bench and what players are on the pitch, the Irish are always difficult to play."
Germany are missing injured winger Marco Reus and striker Miroslav Klose while Ireland captain Robbie Keane is a doubt with an ankle problem.
Austria and Sweden are locked in a battle for second place, with the Scandinavians seemingly in pole position as they sit three points above the third-placed Austrians.
But the rivals meet in Solna with Austria goalkeeper Robert Almer insisting the race to finish runners-up is still open.
"The opportunities are still there. We've got to get at least a point in Sweden and then beat the Faroe Islands. Our fate is still in our hands if we win both matches," Almer said.
In Austria's favour is that Sweden complete their Group C campaign against Germany.