The hosts are currently second in Group H and could end the night topping the group if results go their way, whilst Moldova are fifth having collected five points from their opening seven fixtures.
Caras declared his delight at being able to bring his squad to a stadium such as Wembley, but does not envisage them pulling up any trees in terms of shock results.
"I am very happy to be here," he said.
"There have been a lot of great players and great teams in this world who have never had the luck to play in this stadium but we are now amongst the lucky ones to play an official game in this stadium.
"I was talking about the lucky parts of the draw but the bad one is that the other team, England, are far too good for us, unfortunately.
"In football a lot of things are possible and both teams have their chances. I do realise that our chances are very, very small - that is hard to accept but it is like this.
"We will try very hard tomorrow [Friday], I will tell you that, but we will see the outcome tomorrow [Friday] on the pitch."
England will go in to the match without a number of their regular line-up due to injuries but even the prospect of facing a team missing the likes of Wayne Rooney does not fill Caras with hope.
"We know that the England manager had a great squad, I know there are a lot of injured players but they can be replaced quite well in such a squad," the 62-year-old added.
"Maybe some other teams, the ones who are a bit closer to the level of England, would be able to cause them trouble but I don't think we will be able to do this."
Friday's fixture will see England take to the field for the first time since new Football Association chairman Greg Dyke set the challenge of winning the 2022 World Cup in Qatar.
Caras feels Roy Hodgson's squad is good enough to win the tournament even before Dyke's self-imposed deadline.
When asked if England would have to be considered contenders, Caras replied. "Of course, why not?
"The English Premier League is one of the best in the world and most of the English national players play in the Premier League - I really don't see a reason why England should not have a chance to win it."