Fener beat the Cypriots 1-0 a fortnight ago without Meireles, amongst others, and can move to the brink of qualification to the knockout stages should they win again on home soil.
Meireles has been out of action for a month with a thigh injury picked up on national team duty with Portugal and, while he has returned to training this week, the midfielder is set to be held in reserve.
With Fener struggling domestically Kocaman suggested Meireles, who signed from European champions Chelsea in the summer, would most likely be saved for the weekend visit of Orduspor.
"I want to see Raul Meireles in training before I decide what to do," Kocaman told the club's official website.
"It probably makes more sense to keep him to take part fully in the match against Orduspor."
Fener should, however, get an injury boost with veteran defender Joseph Yobo set to return from a knee problem while Mehmet Topal (calf) is back after missing the match in Cyprus.
"Mehmet Topal and Joseph Yobo seem ready to return," said Kocaman, who also fended off questions about whether out-of-form winger Milos Krasic would be included.
"Everything will become clearer after the final training session," he stressed.
The Turkish side took a stranglehold over Group C after Egemen Korkmaz's 72nd-minute header secured their 1-0 win over AEL a fortnight ago.
Fener are on seven points at the half-way stage, three points ahead of Marseille and Borussia Monchengladbach who meet in the group's other game tomorrow.
Victory would therefore move Kocaman's side at least five points clear of third place with two games remaining.
"We want to strengthen our position by reaching 10 points," Kocaman said.
"This can provide a great advantage for us especially because slowly our players will start coming back.
"If we can do that then hope will increase for tomorrow [Thursday] and the day after tomorrow [Friday]."
AEL arrived in Istanbul with just a single point from their opening three games and having lost their only away date 5-1 to Marseille.