For the first time since 1994, Portugal will dominate the Europa League with three clubs in contention to make the semi-finals of the Europa League.
If Braga and beat Dynamo Kyiv and Benfica knock out PSV Eindhoven, two of them will meet in the semi-finals, which would guarantee a Portuguese team in the finals of the competition.
PSV will look to repeat their previous win over Benfina in the 1987/88 European Champions Club Cup final, as the Dutch side triumphed on penalties.
Elsewhere, Porto will look to continue their unbeaten streak against Russian clubs against Spartak Moskva, nad the winner of this tie could face either La Liga side Villarreal or Dutch champions FC Twente.
The Yellow Submarines will feel confident of their chances, especially with Giuseppe Rossi in fine fettle, the striker having scored eight goals to become the competition's leading scorer so far.