The Real Madrid midfielder made the last of his 20 appearances for Germany in the Euro 2012 qualifier against Austria in June.
He was left out of the Germany setup for a series of friendly matches in August while injury prevented him from being called up for September's Group A qualifying matches.
The 24-year-old has returned to the fold for the upcoming Group A games against Turkey and Belgium, but in his absence the likes of Bastian Schweinsteiger, Mario Gotze, Toni Kroos and Andre Schurrle have shone, leading to suggestions that Khedira is no longer a first choice under coach Joachim Low.
But Khedira branded those suggestions "disrespectful" in an interview with Sport Bild magazine.
He said: "I have found this whole discussion very interesting. People have started to talk about me, about somebody who could not even take part, about somebody who has played non-stop in the national team for years - and pretty well at that - and about somebody who is a regular at Real Madrid.
"I find it a shame. I even think it is disrespectful to talk about me like that in my absence. That is not fair given my performances in recent years."
Despite the doubts about his international future, Khedira is nevertheless in line to return to Low's line-up on Friday with Kroos ruled out by injury.