The Italian side holds a 3-1 aggregate lead over Chelsea and they go into the game on the back of several Serie A victories, including the recent 6-3 drubbing of Cagliari.
Lavezzi has found the net in his last five games for Napoli and Cannavaro has full confidence in the Argentinean striker's ability to cause problems for their Premier League opponents.
"He is a leader and at times, he simply cannot be marked. He can really put the Chelsea defence in crisis," he said to Rai Tre.
The experienced central defender revealed that Napoli go into the game assured of their abilities, and the team will not shrink under the pressure of playing away at Stamford Bridge.
"We will play our game at Stamford Bridge and will certainly give our all. The real Napoli has been back for a while now as we discovered our determination and desire to win," Cannavaro stated.
The second-leg of the Champions League round-of-16 tie between Chelsea and Napoli will take place this Wednesday.