Maradona, the legendary World Cup-winning Argentinean, will forever be revered in Naples after inspiring the Italian club to two Serie A titles and a UEFA Cup win between 1987 and 1990.
Aguero will step into his shadow as City take on Napoli at the San Paolo Stadium looking to secure a place in the knockout stage of the Champions League.
Aguero has made a fine start at City since a £35million summer move from Atletico Madrid, scoring 11 times in 15 appearances, but the 23-year-old still dreams of reaching his compatriot's heights.
"In the past he told me everything about Napoli, and I have also seen on TV what he did, how important he was for the fans," he said.
"This is matter of pride for me because I am Argentinean. It is my dream, doing what Maradona did for Napoli, doing the same for Manchester City.
"But I don't want to talk about myself, it is important Manchester City do well as a team."
Maradona will not be at the game following the recent death of his mother.
Aguero said: "I couldn't speak to him because of the situation, the loss of his mother. I just want to send the best wishes to him at this moment."
City can secure a place in the last 16 with victory on Tuesday but anything less could leave them facing a tricky final group game.