Moyes has long been viewed as a Briton who could make the transition to the highest form of club competition which, Sir Alex Ferguson apart, has tended to be the preserve of overseas bosses.
Now Moyes has his chance.
As Ferguson's successor, the Scot will lead United into their latest campaign, which opens against Bayer Leverkusen at Old Trafford on Tuesday.
"I am really excited to be involved in it," Moyes told MUTV.
"I have been in the Champions League before but I have not made the group stage.
"I had quite a few episodes in the Europa League, which were good, but nothing at the level of the Champions League.
"We will do our homework to make sure we are as prepared as we can be."
Leverkusen will not be remembered with any fondness by United fans since it was the Germans who dumped them out at the semi-final stage in 2002 when it seemed Ferguson was destined to take the Red Devils to his native Glasgow to face Real Madrid.
The exit of star man Michael Ballack cost Leverkusen their momentum but after a couple of seasons in the wilderness, former Liverpool defender Sami Hyypia guided the club into third spot last term, just a point adrift of Borussia Dortmund.
Leverkusen are presently unbeaten in the Bundesliga, so Moyes accepts they represent another awkward hurdle in a less-than-straightforward group that also includes Shakhtar Donetsk and Real Sociedad.
He cannot escape the thrill though, which was even evident as the 50-year-old got wrapped up in the draw.
"It was the first time I have been involved in a draw at that level," said Moyes.
"When the names came out there were some that I didn't want and others I would have been happy with.
"Relatively I am quite pleased. To draw Real Sociedad out of the last pot was a tough one.
"They have done well in Spain this year and had a great result against Lyon to get into the group stage.
"That put a little bit of a downer on it. In addition, Leverkusen are doing well in Germany and we also have the long trip to Donetsk."
Moyes didn't get the tie he dreamed of, a trip to his native Glasgow to face the club he started his career with.
However, he is ready for the challenge, which he missed out in 2005 when Everton were beaten by Villarreal in the final qualifying round.
"I would have loved to have gone back to Celtic," said Moyes.
"That would have been a hard game but it would have been great for me.
"Overall though I am pleased. It is a pretty good draw but we have to be mindful that we do the job right with the games."
United will be without winger Nani though.
The Portugal international has to serve a one-match suspension following his controversial red card against Real Madrid at Old Trafford last season.