Massimiliano Allegri is expected to stick with the 3-5-2 formation. His only injury absentees are central defender Martin Caceres (ankle) and attacking midfielder Paul Pogba (thigh).
Andrea Pirlo will be expected to play in central midfield after returning from a five-week injury lay-off in time for the first leg and playing 70 minutes against Lazio.
“I haven’t decided which formation I will use. If the team defends well, I think it doesn’t really matter if we have three or four at the back,” Allegri said.
“I’m happy about the success the team is enjoying. The lads deserve praise because they’ve shown a lot of maturity.”
Monaco have netted just three times in four Champions League home games this season but can call on one of the tightest defences in Europe, although in midfield it remains to be seen whether captain Jeremy Toulalan (hamstring) and the powerful Geoffrey Kondogbia (ankle) will recover from injury in time to feature.
Further forward, Jardim must decide whether to select the experienced Dimitar Berbatov or the exciting Anthony Martial in attack, or go with both.