Fourteen years ago to the day, coach Thomas Schaaf sat on their bench for the first time and - with a 1-0 victory over Schalke - celebrated a win which virtually ensured their Bundesliga survival.
The longest-serving coach in the German top flight now faces a similar date with destiny, knowing a win would all but wrap up their place in the Bundesliga for another year.
"I am convinced that Thomas will keep us up," Bremen general manager Klaus-Dieter Fischer told the Bild newspaper.
"We were in a much worse situation in 1999 in a greater state of emergency, and Schaaf was an inexperienced coach back then."
Even if Bremen get the win they need to stay up, the season will go down as the worst since Schaaf took charge - leaving his future still in the balance.
"We are going to leave no stone unturned after the season," Fischer added. "Then we will talk about people.
"We are not happy with the players we bought recently, nor are we happy with the young players who have been fed into the first team.
"We've got to discuss all these things."
Frankfurt will not be making life easy for Bremen, however, since they are still in the running for a place in Europe next season.
Three points would secure a Europa League berth and keep them in the running for a Champions League spot going into the final game of the campaign.
"We would be delighted if we were to make it," their coach Armin Veh said. "Qualifying for the Europa League would make all of us really happy."