Gisdol, the fourth coach on the Hoffenheim bench this season after Markus Babbel, Frank Kramer and Marco Kurz, will try to mastermind a Bundesliga victory at home to relegation rivals Fortuna Dusseldorf tomorrow.
Fortuna are one place above the drop zone and nine points ahead of Hoffenheim and the match will be key in the fight for survival.
"I would never make any game out to be a relegation decider," he said.
"I just want to see that the lads put into practice what we have given them to do.
"If they achieve that, then we can see what comes out of it."
While three points would give Hoffenheim some much-needed hope of avoiding relegation, victory for Fortuna would practically see them free of any lingering automatic relegation worries with six games of the season to go.
"The game against Hoffenheim is very important," coach Norbert Meier said.
"We are now on the final straight of the season. It may not be Hoffenheim's very last chance, but a defeat for them would leave them on a slippery slope.
"We, on the other hand, have the chance to distance ourselves further from a direct rival."
Meier is sweating on the fitness of his Australian forward Robbie Kruse, who has a knee injury.
"He's going to make the trip to Sinsheim with us, but we're going to have to wait and see if he can play," he added.
Gisdol is keeping his cards close to his chest, but is expected to make changes to the starting XI.
Sejad Salihovic may return after injury, but Eren Derdiyok, Chris and Vincenzo Grillo are all still injured.