The Foals host Lazio in the first leg of their last-32 tie on Thursday as they look to take a step closer to becoming only the fourth club to win the competition three times, following in the footsteps of European superpowers Juventus, Inter Milan and Liverpool.
However, before they can even contemplate how to handle the Serie A high-flyers, Favre says he is busy enough trying to find a way to combat one of the Bundesliga's leading clubs.
"We are just looking from game to game," he said. "Our full concentration is on Leverkusen.
"From Sunday, we can then concern ourselves with Lazio."
Bayer surrendered second place to Borussia Dortmund last weekend after losing 3-2 at home to the reigning champions.
Despite the result though, Favre was impressed the way Bayer played in that match and is well aware of the threat they pose to his side.
"That game was an advert for the Bundesliga," he said at a press conference. "Leverkusen played really well and came back after going behind, and they did not have to lose the game.
"Bayer have a team which is very well organised and, after losing the ball, they are very dangerous on the counter-attack."
The man to watch is Bayer's top goalscorer Stefan Kiessling, and that could be a job for Martin Stranzl, who is set to make his first start of 2013 after recovering from injury.
Kiessling, meanwhile, has set his sights on an away win to get straight back on track following their disappointing defeat to Dortmund.
"We've got to look at the positives and now we want to start a new winning streak," he said.
"It's a very important game. We have to get the three points otherwise things could start to get uncomfortable with two defeats in a row."