A 3-0 win over Stuttgart on Sunday lifted Freiburg to sixth in the Bundesliga table, a position which would earn them a place in next season's Europa League.
And after picking up 14 points from their last seven games, Streich sees no reason why his south-west outfit should stand in awe of the league leaders on Wednesday night.
"We are happy to be a small club, we feel good that way, but we don't always want to be small," Streich told a press conference.
"We want to grow bigger. My lads have no fear, I know that. We always want three points, anything else would be bad anyway."
Streich says that his side can play without any pressure on Wednesday, given that all the expectations are for a Bayern victory, while a seven-point cushion on the bottom three means they do not have to look over their shoulders too much.
"I am incredibly delighted that we don't have our backs to the wall," Streich added. "Our quality of life is better and we are sleeping better, and that does you good."
Streich's achievement in lifting Freiburg to sixth place after 13 games of the season is not lost on Bayern coach Jupp Heynckes either.
"Freiburg's best man is sat on their bench," he said. "He (Streich) has not only worked on the foundations, but he has also started a revival at Freiburg.
"He is down to earth, competent and has his team play modern football."
Nevertheless, Bayern's aim cannot be any lower than getting three points to give them a comfortable margin over Borussia Dortmund before the two giants of German football meet at the Allianz Arena on Saturday.
"I am only focusing on Freiburg," Heynckes told a pre-match press conference. "They are in good form."
Heynckes is still without the injured Arjen Robben, but Mario Gomez is an option again after marking his return after a four-month injury absence with a goal at the weekend.