Frankfurt travel to face league leaders Bayern Munich as the side who, along with Schalke, are currently Bayern's nearest rivals in the Bundesliga.
Seven points separate the two clubs with Bayern able to take another big step towards their first piece of silverware in three years by winning for the 10th time in 11 games this season, but Frankfurt coach Armin Veh claims there is a much larger divide between the two clubs.
"(Javi) Martinez cost (Bayern) 40 million euros and he probably earns 10 million a year in wages - with those 50 million euros for just one Bayern player we could afford to pay the wages of our whole team for two years," Veh said.
"That goes to show that we are not on a level playing field. You cannot compare us with Bayern."
Indeed, Veh has dismissed his side's chances of victory before even travelling to the Bavarian capital, something he is still not sure is worth the effort.
"I have wondered whether it makes any sense at all me travelling," he told the Bild newspaper. "I have never won at the Allianz Arena."
Yet Veh will be there in person on Saturday as his side tries to create the next upset in a league which has proven to be full of surprises in recent years, not least when Veh himself led Stuttgart to the Bundesliga title in 2007.
His former club are now marching up the table again after a difficult start to the season and they can break into the top six with a win over fellow Europa League participants Hannover on Sunday.
In fact, disregarding Bayern, the race for places in Europe next season has rarely been so intense after almost a third of the season with more than half of the Bundesliga still in with a realistic chance of finishing inside the top six.
On the flip side, such a tight league means that those very same clubs must also keep looking over their shoulders.
Apart from Bavarian rivals Augsburg and Greuther Furth, with only one win each all season and tough games against Borussia Dortmund and Borussia Monchengladbach on Saturday and Sunday respectively, any other club could easily be dragged into danger.
Wolfsburg, who host Bayer Leverkusen on Sunday, are currently occupying 16th place, but Fortuna Dusseldorf and Hoffenheim remain in precarious positions ahead of their meeting at the Dusseldorf Arena on Saturday.
Elsewhere, Schalke host Werder Bremen and Freiburg entertain Hamburg in Saturday's other fixtures.
On Friday, Mainz climbed up to fifth with a 2-1 win over Nuremberg.
Saturday's Bundesliga Fixtures
Sunday's Bundesliga Fixtures
Friday's Bundesliga Results