Franck Ribery scored both goals for the Bavarians, who are now just one win away from breaking the record for consecutive victories at the start of the seaso, which they share with Mainz and Kaiserslautern.
The Frenchman struck first in the 19th minute and then sealed the win in the 47th as Bayern bounced back from their only defeat in all competitions, at BATE Borisov in the Champions League in midweek.
The Ribery show got under way in the 19th minute when he raced into the penalty area and, with his left foot, threaded the ball through the legs of Hoffenheim goalkeeper Koen Casteels.
With a visit to the city's annual Oktoberfest beer festival the reward for another win, Bayern were up for the occasion.
Ribery missed the chance to double their lead just before the break, but he made amends shortly after the restart.
Toni Kroos failed to connect with Mario Mandzukic's cross, but the ball got caught up between his legs, giving him a second chance to set up Ribery to double Bayern's lead.
Hoffenheim coach Markus Babbel, who was on the receiving end of a 4-0 defeat and a 7-1 hammering with Hertha Berlin and Hoffenheim against Bayern last season, may have started to fear the worst with much of the second half still to be played.
But, aside from a header wide from Javi Martinez, Bayern took their foot off the gas, closing out the game with ease.