Hertha need to at least match the result of Cologne, who travel to Freiburg, to keep their hopes of avoiding relegation alive, otherwise Otto Rehhagel's side could follow Kaiserslautern down into the second division with a game still to be played.
To get them focused on the task, Rehhagel has whisked his side out of the capital for three days to a venue just up the road from the Arena AufSchalke.
"I still believe that we will avoid relegation," Hertha defender Maik Franz told the Berliner Morgenpost.
"We have realised that things have not been ideal in the second half of the season. Nevertheless, I feel that the character of the side is fine.
"We are going into a training camp to mobilise all of our strength and to pull even closer together."
While Hertha and Cologne are battling to avoid relegation, Kaiserslautern will play their last home game in the top flight on Saturday with champions Borussia Dortmund paying them a visit.
"We want to win back some of the pride and honour that we have lost," defender Mathias Abel told the club's website.
"We will all do whatever we can to beat the champions and at least give something back to our fans.
"We know that even a win will not be any consolation, but we would at least like to say goodbye with a win."
Augsburg and Hamburg could theoretically still be dragged into the bottom three, but they know that a win at Borussia Monchengladbach or at home to Mainz respectively would secure their place in the top flight with a game to spare.
At the other end of the table, with Dortmund securing the title last weekend and Bayern Munich guaranteed second place, the battle for third involves Schalke and Gladbach.
Behind them, Stuttgart can clinch fifth spot with a win at Bayern, assuming Bayer Leverkusen fail to beat Hannover, who in turn need a win to secure their place in the Europa League.
Elsewhere, Wolfsburg and Werder Bremen can both wave Europe goodbye without a win while Hoffenheim's outside chance of reaching the top seven depends on them beating Nuremberg at the Rhein-Neckar Arena.
Saturday's Bundesliga Fixtures