Freiburg have a five-point advantage over the Red Devils at the bottom of the Bundesliga table and a win at the Dreisamstadion could take them out of the bottom three this weekend.
However, Streich has dismissed claims that Saturday's clash is a relegation six-pointer.
"For as long as I have been involved in football, there have only ever been three points at stake," he said at a press conference.
"Even against Kaiserslautern, there are only three points available."
A win would give Freiburg an eight-point cushion over one of their rivals at the bottom of the table, which Streich admits "would be a lot", but he is not putting any pressure on his team.
"We don't have to win it," he said.
"The only thing in life that you inevitably have to do is die, but we don't inevitably have to win this game."
Kaiserslautern attempted to avert what seems inevitable for them this season by dismissing Marco Kurz after a run of 16 games without a win.
Krassimir Balakov has been appointed to try to save the club from relegation over the last eight games of the season.
"We have no time to lose," he told his club's website.
"We have got to be motivated from the very beginning. I have enough information to prepare my team in the best possible way.
"Of course we are not going to radically change the style of play in such a short space of time, but we will touch on a few basic things.
"We will do all we can to get out of the lower regions of the league and we want to make a start against Freiburg."
Johannes Flum is the home side's only doubt with a muscular injury putting his appearance at risk while Balakov's first team selection will not make any difference to Streich's plans.
"We don't know how his team will play, but that doesn't change anything for us," said the Freiburg coach.