Klopp told a reporter from Germany's ZDF channel "if you ask stupid questions, you'll get stupid answers", as he ridiculed him for suggesting Dortmund have nothing to play for in the second leg of their Champions League tie with Real Madrid next week.
Only a few weeks ago, Klopp had a verbal battle with former Bayern Munich goalkeeper Oliver Kahn on the same channel after he gave his opinion on an ongoing feud between the two clubs.
The Dortmund coach has been accused of being a bad loser by the German media, and he has the perfect remedy for that: winning. Starting with Saturday's home clash with Wolfsburg.
"We've just got to deliver the results and then everything's fine," Klopp said on Friday. "This is an absolutely crucial game and Wolfsburg are in good form.
"If we can maintain our gap over them, then that would certainly be a big step."
Following Wednesday's 3-0 defeat at Real Madrid, Dortmund's hopes of progressing in the Champions League look slender, which is why ensuring a top-three finish is the Westphalians' new priority.
They lead Wolfsburg, who lie fifth, by eight points and could all but seal a top-four berth with victory.
"My lads know what's at stake," Klopp said. "We're going to be ready."
So too are Wolfsburg, who are keen to spoil the 40th birthday celebrations of Dortmund's Westfalenstadion home.
"I still think they have one of the most beautiful stadiums in Germany," said their coach Dieter Hecking.
"It's always a great challenge to play there, but there is definitely the chance for us to come away with something."
Hecking loses regular goalkeeper Diego Benaglio due to injury, meaning Max Grun will have the job of keeping out Dortmund's top-scorer Robert Lewandowski, who is available after suspension ruled him out in Madrid.