The Wolves' impeccable home form was the key to winning the Bundesliga title in 2009, yet since then they have struggled to intimidate visiting rivals.
Last season, Wolfsburg's home form proved to be their Achilles heel with only relegated Greuther Furth having a worse record on home turf, but Hecking hopes things will change this season.
"We've got to make sure we play on the field in such a way that we get the fans behind us," he said.
"We have got to show that we desperately want to win this home game. I'm sure our fans know all too well what we need from them."
Hecking will be without the suspended Maximilian Arnold and Timm Klose, but he could yet count on the services of Luiz Gustavo.
The Wolves on Friday completed the signing of the Brazilian from Bayern Munich and he could be thrown straight into action having returned from international duty on Thursday.
Schalke won 4-1 in Wolfsburg last season with Klaas-Jan Huntelaar on target in that win.
He scored two in last weekend's 3-3 draw with Hamburg and is looking forward to adding to that on Saturday, although he stresses that the result is more important.
"Of course I'd be delighted if I scored again, but winning is what matters," he said on his club's website. "I want to play my part in that, whichever way I can."
Four days later, Schalke begin their Champions League campaign with the first leg of their play-off tie against PAOK, but the Dutch forward says he has not given that game much thought yet.
"We're focusing solely on the Bundesliga," he said.
"We desperately want to get three points in Wolfsburg and we aren't going to be distracted by anything else."